Our Story

In 2019, we launched our firm by focusing on the entrepreneurial community at Caltech. There we have found core science breakthroughs, deep tech innovation and a highly supportive environment for a new generation of founders.

In our first four years, we have invested in over 30 companies, forming our initial portfolio of category creating companies that leverage proprietary IP,  AI, machine learning and other advanced technologies to move to market faster and more efficiently than ever.

Our Investment Model

From sourcing to support, our model is tailored to the needs of high-potential science-driven companies.


01

Connect

Develop deal flow in high quality scientific communities underserved by venture capital

02

Invest

Deploy capital at early stage human and planetary health companies enabled by AI and ML

03

Support

Serve founders and teams with non-science value add including fundraising, marketing, hiring and strategy

Convergent science yields new kinds of companies

Advanced computing power is driving a revolution in higher precision, cross-discipline innovation that moves more efficiently from the lab to the field. We're committed investors for companies leading this change.

Our numbers

Our investment segments represent the core areas where we apply our expertise and strategic insights to deliver optimal value. By focusing on these carefully selected market segments, we identify unique opportunities aligned with our clients' objectives.


$90M

AUM

Three funds to date: Fund One ($25M), Fund Two ($35M) and in early 2024, we closed our first Opportunity Fund at $15M. We also offered additional SPVs for breakout companies.

30+

Portfolio companies

We've invested in more than 30 companies at pre-seed, seed, Series A and Series B rounds. Deep tech that leverages computer science is our core thesis.

100+

Co-investors

Our companies continually attract co-investors from venture and corporate capital. We also regularly provide co-investment opportunities as companies grow and offer new value.

News

Freeflow Expands Into the UCSF Ecosystem

June 2026

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Press Release

Freeflow Ventures Raises $90M In Funding For Early Stage Deep Tech Investments

June 2024

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Investment

Captura

Captura is a revolutionary system for capturing carbon dioxide from ocean water at scale.

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Investment

Holoclara

Holoclara's mission is to restore missing components of the human molecular legacy.

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Founder's Session

Iambic Therapeutics

Iambic Therapeutics has created a disruptive platform for small-molecule drug discovery by harnessing leadership in physics-informed AI and tightly integrating AI-driven design and experimental execution.

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Founder's Session

Hydrosat

Hydrosat uses satellite imagery to provide geospatial intelligence for food security, public safety, and the environment.

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News

Architecting the Big Capital Raise: Learnings from Deep Tech Venture

April 2023

On the long path to success, a fork in the road many startups face is securing the right investment at the right time. We believe the next trillion dollar companies come from the deep tech themes of Human and Planetary Health.

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Founder's Sessions

We regularly post content and news from our portfolio companies and the Freeflow team.

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